Division of Gynecology, Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.
Fertil Steril. 2011 Jan;95(1):290.e17-9. doi: 10.1016/j.fertnstert.2010.05.051.
To describe a rare anomaly of the female reproductive tract and review the embryology associated with the defect.
Case report and review of the literature.
Major academic medical center.
PATIENT(S): A 14-year-old girl with two hemiuteri lacking any communication with a single normal midline cervix and vagina.
INTERVENTION(S): Diagnostic laparoscopy with chromopertubation to identify the anomaly and subsequent bilateral supracervical hemihysterectomies.
MAIN OUTCOME MEASURE(S): Incidence, pathogenesis, fertility implications, and treatment options for patients with congenital defects in the upper vagina, cervix, and uterus.
RESULT(S): Based on classic embryology, the lower vagina forms from the urogenital sinus while the upper vagina, cervix, and uterus form from the müllerian ducts. If a cervix is present, then the upper vagina and uterus are also usually present and should communicate.
CONCLUSION(S): This anomaly cannot be fully explained by traditional embryologic developmental theory. It is likely that an insult occurred between 9 weeks, when the uterovaginal canal is formed, and 12 weeks, when the müllerian ducts fuse.
描述女性生殖道的一种罕见异常，并复习与该缺陷相关的胚胎学。
病例报告和文献复习。
主要学术医疗中心。
一名 14 岁女孩，两侧半子宫没有任何与单一正常中线宫颈和阴道相通。
诊断性腹腔镜检查伴色度插管以识别异常，随后行双侧宫骶部半子宫切除术。
先天性上生殖道、宫颈和子宫缺陷患者的发病率、发病机制、生育影响和治疗选择。
根据经典胚胎学，下生殖道由尿生殖窦形成，而上生殖道、宫颈和子宫由苗勒管形成。如果存在宫颈，则通常也存在上生殖道和子宫，并且它们应该相通。
这种异常不能用传统的胚胎发育理论完全解释。很可能在 9 周（此时形成阴道子宫管）和 12 周（此时苗勒管融合）之间发生了某种损伤。
Zotero 插件