Department of Gynaecology, Universite Libre de Bruxelles Hopital Erasme, Brussels, Belgium.
Eur J Obstet Gynecol Reprod Biol. 2010 Nov;153(1):8-11. doi: 10.1016/j.ejogrb.2010.05.024. Epub 2010 Jun 19.
Low-grade squamous intraepithelial lesions (LSIL) are frequently found during cervical cancer screening. Usually they are associated with a human papillomavirus (HPV) infection. Does the high-transmission rate of HPV infection to the male partner represent a clinical risk for him? Are preventive measures to be taken to prevent the occurrence of male diseases? More than 80% of all LSIL are associated with HPV infections. The prevalence of HPV infection in males can range up to 40%, with 60% of the male partners of LSIL female patients presenting with penile flat lesions. The spontaneous cure rate for male infections is very high (90% at 5 years) but negative consequences in females (cervical high-grade lesion and cervical cancer) are frequent. Their male counterparts are far rarer but in some patients can require deleterious treatment. Transmission prevention by the use of condoms and circumcision is discussed. The effectiveness of HPV vaccination in this situation has not been validated.
低度鳞状上皮内病变（LSIL）在宫颈癌筛查中经常发现。通常与人类乳头瘤病毒（HPV）感染有关。HPV 感染给男性伴侣的高传播率是否代表他的临床风险？是否需要采取预防措施来防止男性疾病的发生？超过 80%的 LSIL 与 HPV 感染有关。男性 HPV 感染的患病率可高达 40%，LSIL 女性患者的 60%男性伴侣出现阴茎扁平病变。男性感染的自发治愈率非常高（5 年内为 90%），但女性的不良后果（宫颈高级别病变和宫颈癌）很常见。他们的男性伴侣则要罕见得多，但在某些患者中可能需要进行有害治疗。讨论了通过使用避孕套和割礼来预防传播。在这种情况下，HPV 疫苗接种的有效性尚未得到验证。
Eur J Obstet Gynecol Reprod Biol. 2010-6-19
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