Lu Siyuan, Cal Shaoxi, Jiang Jiahuan
College of Bioengineering, Chongqing University, Chongqing 400044, China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2010 Jun;27(3):675-9.
Microfluidic chip is a novel technology platform, in which microchannels are fabricated in different materials. The ability to precisely control the microflows makes it possible to mimic the microenvironment of cells in physiological or pathological states, which provides many distinct advantages for cell research. In this paper are reviewed the design and fabrication of microfluidic chip, the application of microfluidic chip in cell culture and cell researches; the enormous advantages of microfluidic chips in precise experimental control of the cellular microenvironment are introduced.
微流控芯片是一种新型技术平台,其中微通道由不同材料制成。精确控制微流的能力使其能够模拟细胞在生理或病理状态下的微环境,这为细胞研究提供了许多独特优势。本文综述了微流控芯片的设计与制造、微流控芯片在细胞培养和细胞研究中的应用;介绍了微流控芯片在精确控制细胞微环境实验方面的巨大优势。