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超声乳化白内障吸除术联合人工晶状体植入术治疗葡萄膜炎。

Phacoemulsification with intraocular lens implantation in patients with uveitis.

机构信息

Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

J Cataract Refract Surg. 2010 Aug;36(8):1283-8. doi: 10.1016/j.jcrs.2010.02.019.

DOI:10.1016/j.jcrs.2010.02.019
PMID:20656149
Abstract

PURPOSE

To evaluate the outcomes of phacoemulsification with intraocular lens (IOL) implantation in eyes with uveitis.

SETTING

Tertiary care center, Chandigarh, India.

METHODS

Consecutive patients with uveitis and visually significant cataract were retrospectively studied for outcomes after phacoemulsification and implantation of a poly(methyl methacrylate) (PMMA) or a hydrophobic acrylic IOL.

RESULTS

The study comprised 108 eyes of 81 patients (50 women, 31 men) with a mean age of 42.3 years +/- 13.98 (SD) (range 18 to 75 years) and a mean follow-up of 21.95 months (range 12 to 66 months). Etiology of uveitis was presumed tuberculosis (n = 24), Vogt-Koyanagi-Harada syndrome (n = 9), Behçet disease (n = 8), sarcoidosis (n = 5), ankylosing spondylitis (n = 4), serpiginous choroiditis (n = 2), and idiopathic (n = 29). The mean corrected distance visual acuity (CDVA) was 1.08 +/- 0.85 logMAR preoperatively and 0.42 +/- 0.78 D logMAR postoperatively; the improvement was statistically significant (P<.001, paired t test); Seventy-seven eyes (71.30%) achieved a CDVA between 0.00 logMAR and 0.30 logMAR (20/20 to 20/40 Snellen). Posterior capsule opacification (PCO) requiring neodymium:YAG capsulotomy occurred in 31 eyes (28.70%); posterior synechias in 27 eyes (25.00%); cystoid macular edema (CME) in 23 eyes (21.30%); recurrent uveitis in 6 eyes (5.55%); and epiretinal membrane formation, glaucoma, and iris bombe in 5 eyes (4.63%) each.

CONCLUSIONS

Phacoemulsification with IOL implantation improved vision in most patients with coexisting cataract and uveitis. The main complications affecting visual outcomes were macular involvement, CME, PCO, and glaucoma.

FINANCIAL DISCLOSURE

No author has a financial or proprietary interest in any material or method mentioned.

摘要

目的

评估超声乳化白内障吸除术联合人工晶状体(IOL)植入治疗葡萄膜炎相关白内障的效果。

设置

印度昌迪加尔的三级护理中心。

方法

回顾性分析了超声乳化白内障吸除术联合聚甲基丙烯酸甲酯(PMMA)或疏水性丙烯酸酯 IOL 植入治疗葡萄膜炎合并明显影响视力的白内障患者的结局。

结果

该研究纳入了 81 例(50 名女性,31 名男性)108 只眼的临床资料,患者平均年龄为 42.3 岁±13.98(标准差)(18 至 75 岁),平均随访 21.95 个月(12 至 66 个月)。葡萄膜炎病因推测为结核(n=24)、Vogt-Koyanagi-Harada 综合征(n=9)、Behçet 病(n=8)、结节病(n=5)、强直性脊柱炎(n=4)、匐行性脉络膜视网膜炎(n=2)和特发性(n=29)。术前平均矫正视力(CDVA)为 1.08±0.85 logMAR,术后为 0.42±0.78 D logMAR;术后视力改善有统计学意义(P<.001,配对 t 检验);77 只眼(71.30%)术后 CDVA 为 0.00 logMAR 至 0.30 logMAR(20/20 至 20/40 视力)。31 只眼(28.70%)需要行钕:钇铝石榴石(Nd:YAG)后囊膜切开术以治疗后发性白内障;27 只眼(25.00%)发生后发性粘连;23 只眼(21.30%)发生黄斑囊样水肿(CME);6 只眼(5.55%)发生葡萄膜炎复发;5 只眼(4.63%)分别发生视网膜前膜形成、青光眼和虹膜膨隆。

结论

超声乳化白内障吸除术联合 IOL 植入术改善了合并白内障和葡萄膜炎患者的视力。影响视力结果的主要并发症为黄斑受累、CME、后发性白内障和青光眼。

利益冲突

无作者在文中提到的任何材料或方法上存在经济或个人利益。

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