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首例波兰前臂移植——最终报告(4年后的结果)。

First Polish forearm transplantation - final report (outcome after 4 years).

作者信息

Jablecki Jerzy, Kaczmarzyk Leszek, Domanasiewicz Adam, Chelmonski Adam, Boratynska Maria, Patrzalek Dariusz

机构信息

Department of General Surgery, Subdepartment of Replantation of Limbs, St Jadwiga Hospital, Trzebnica, Poland.

出版信息

Ann Transplant. 2010 Apr-Jun;15(2):61-7.

Abstract

BACKGROUND

Hand transplantation (HTx) presents an exceptional reconstructive solution for hand amputees. Relatively few patients qualify for such an operation - generally healthy patients suffering from a serious disturbance of body integrity.

CASE REPORT

We present a patient 48 months after unilateral transplantation of an allogenic forearm. Clinical course, laboratory results, function of the graft, and quality of life of the patient are analyzed. These findings are compared with those achieved by 2 other patients - recipients of allograft forearm transplanted on the same zone in Lyon 2002, and Louisville 2001. The patient suffered no post-transplantation infections, had 1 episode of rejection - I degrees . Except for mild diabetes, no disturbances of internal organs were observed. Total active motions of fingers (TAM) equaled 53% of fingers of unaffected hand. The functional evaluation by SF 36 is 53; by DASH - 92; Chen's score system rates our patient as II (good); CFSS score system - 84 points (excellent result). His functional result is similar to that achieved by 2 others mid-forearm recipients.

CONCLUSIONS

The upper limb transplant performed on a functionally unfavorable zone of the mid-forearm has greatly increased patient's quality of life.

摘要

背景

手部移植(HTx)为手部截肢患者提供了一种特殊的重建解决方案。符合这种手术条件的患者相对较少——通常是身体完整性受到严重干扰的健康患者。

病例报告

我们展示了一名患者在异体前臂单侧移植48个月后的情况。分析了临床病程、实验室检查结果、移植功能以及患者的生活质量。将这些结果与另外两名患者的结果进行比较——这两名患者分别于2002年在里昂和2001年在路易斯维尔接受了在同一区域移植的异体前臂。该患者术后未发生感染,有1次I度排斥反应。除轻度糖尿病外,未观察到内脏器官有异常。手指总主动活动度(TAM)相当于未受影响手手指的53%。SF 36功能评估为53;DASH为92;陈式评分系统将我们的患者评为II级(良好);CFSS评分系统为84分(优秀结果)。他的功能结果与另外两名前臂中段接受者的结果相似。

结论

在前臂中段功能不利区域进行的上肢移植极大地提高了患者的生活质量。

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