细菌性脑膜炎 9 年后的认知功能和生活质量。

Cognitive functioning and quality of life nine years after bacterial meningitis.

机构信息

Department of Neurology H2, Academic Medical Center, Amsterdam, The Netherlands.

出版信息

J Infect. 2010 Oct;61(4):330-4. doi: 10.1016/j.jinf.2010.07.006. Epub 2010 Jul 24.

DOI:10.1016/j.jinf.2010.07.006

PMID:20659499

Abstract

OBJECTIVE

To examine recovery of psychological functioning nine years after meningitis.

METHODS

In a follow-up study, cognitive functioning and quality of life were evaluated in 28 adults 8-10 years after recovery from bacterial meningitis (n=17 due to Streptococcus pneumoniae; n=11 due to Neisseria meningitidis), and 13 controls. Test results were compared with those performed one year after the disease. All patients were well recovered at discharge (defined as a score on the Glasgow Outcome Scale of 5), but some pneumococcal patients still showed cognitive slowness and low quality of life one year after bacterial meningitis.

RESULTS

At follow-up, psychological functioning and quality of life of patients and controls were similar. On group level, cognitive functioning had normalized. This was also true for patients after pneumococcal meningitis, although some cognitive slowness persisted on an individual level.

CONCLUSION

Psychological functioning continues to improve slowly during the first decade after bacterial meningitis.

摘要

目的

探讨脑膜炎九年后心理功能的恢复情况。

方法

在一项随访研究中，对 28 名细菌性脑膜炎（17 名由肺炎链球菌引起，11 名由脑膜炎奈瑟菌引起）康复 8-10 年后的成年人的认知功能和生活质量进行了评估，并与 13 名对照组进行了比较。测试结果与疾病发生一年后的结果进行了比较。所有患者在出院时均已完全康复（格拉斯哥预后评分 5 分），但一些肺炎球菌患者在细菌性脑膜炎一年后仍表现出认知迟缓、生活质量低。