味觉遗传学：甜蜜的 gustducin！
Gustation genetics: sweet gustducin!
机构信息
Monell Chemical Senses Center, Philadelphia, PA 19104, USA.
出版信息
Chem Senses. 2010 Sep;35(7):549-50. doi: 10.1093/chemse/bjq059. Epub 2010 Jul 21.
Abstract
Two recent studies, the second of which is reported herein, provide evidence that genetic variation in the sweet receptor subunit, TAS1R3, and the second messenger, gustducin (GNAT3), affect the ability of people to correctly sort ascending concentrations of sucrose. These findings raise questions about how variation in the TAS1R3 and GNAT3 gene shape the human sweet tooth and its unwelcome consequences, diabetes and obesity.
摘要
最近的两项研究，其中第二项研究在此报道，提供了证据表明甜味受体亚基 TAS1R3 和第二信使 gustducin (GNAT3) 的遗传变异影响人们正确分类蔗糖递增浓度的能力。这些发现提出了关于 TAS1R3 和 GNAT3 基因变异如何塑造人类的嗜甜特性及其不受欢迎的后果，如糖尿病和肥胖的问题。
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