Florida Atlantic University School of Social Work, Boca Raton, FL 33431, USA.
Clin J Pain. 2010 Oct;26(8):647-55. doi: 10.1097/AJP.0b013e3181e94240.
The aim of the study was to identify physical, psychological, and social risk factors associated with opioid medication misuse among community-dwelling older adults with chronic pain.
Using a cross-sectional research design, a confidential survey was administered at 11 outpatient clinics affiliated with the Baltimore Veterans Affairs Medical Center and the University of Maryland Medical System. A sample of 163 older adults (response rate 80.7%) with chronic pain and receiving opioid medications provided demographic information and responded to survey items. Severity of pain, alcohol problems, physical disability, depressive symptoms, spirituality, social support, and social network were assessed. Descriptive statistics and exploratory regression analyses were employed to determine factors independently associated with misuse.
Higher levels of pain severity and depressive symptoms, and lower physical disability scores were significantly associated with increased risk of opioid medication misuse. Alcohol problems, spirituality, social support, and social network were not associated with opioid medication misuse.
High pain intensity scores may indicate undertreatment of pain or may represent a rationalization to justify opioid medication use. Higher levels of depressive symptoms have been noted in the chronic pain population and may contribute to misuse of opioid medications for psychic effects. Less physically disabled persons are more likely to misuse opioid medications or older person receiving multiple medications may wish to avoid potential adverse drug effects. While there was an association between lower levels of disability and higher risk for opioid medication misuse, a causal relationship could not be determined.
本研究旨在确定与社区居住的慢性疼痛老年患者阿片类药物滥用相关的身体、心理和社会风险因素。
采用横断面研究设计,在巴尔的摩退伍军人事务医疗中心和马里兰大学医疗系统的 11 个门诊诊所进行了一项机密调查。163 名患有慢性疼痛且正在服用阿片类药物的老年患者(响应率为 80.7%)提供了人口统计学信息,并对调查项目做出了回应。评估了疼痛严重程度、酒精问题、身体残疾、抑郁症状、灵性、社会支持和社交网络。采用描述性统计和探索性回归分析来确定与滥用相关的独立因素。
疼痛严重程度和抑郁症状评分较高,身体残疾评分较低,与阿片类药物滥用风险增加显著相关。酒精问题、灵性、社会支持和社交网络与阿片类药物滥用无关。
高疼痛强度评分可能表明疼痛治疗不足,或者可能代表合理化阿片类药物的使用。慢性疼痛人群中注意到较高水平的抑郁症状,这可能导致为了精神效果而滥用阿片类药物。身体残疾程度较低的人更有可能滥用阿片类药物,或者接受多种药物治疗的老年人可能希望避免潜在的药物不良反应。虽然残疾程度较低与阿片类药物滥用风险较高之间存在关联,但不能确定因果关系。