Department of Cardiology, Kishiwada Tokushukai Hospital, Kishiwada city, Osaka, Japan.
Catheter Cardiovasc Interv. 2010 Aug 1;76(2):214-9. doi: 10.1002/ccd.22445.
The aim of the study was to report the clinical utility of native chronic total occlusion (CTO) recanalization as an endovascular strategy in lower limb bypass graft occlusion.
There is no consensus on the best approach for threatened limbs in patients with graft occlusion.
The subjects were nine consecutive patients with limb-threatening ischemia after bypass graft occlusion. Native CTO recanalization was attempted endovascularly using conventional intraluminal and subintimal angioplasty techniques supported by stents.
The mean age of the bypass grafts was 6.7 +/- 7.3 (range: 1-24) months and the mean number of previous lower limb bypass surgeries was 1.4 +/- 0.5 (range: 1-2). Native CTO recanalization was performed in the iliofemoral (n = 2), iliac (n = 2), superficial femoral (n = 3), popliteal (n = 1), and popliteal-tibial (n = 1) arteries. Technical success was achieved in 89% (8/9) of cases without complications or major adverse cardiovascular events. The ankle-brachial index and skin perfusion pressure of the foot significantly increased after revascularization, with marked improvement of clinical symptoms (Rutherford class: 4.5 +/- 1.1-->0.9 +/- 1.4, P < 0.001). Limb salvage was achieved in all successful recanalization cases during the mean follow-up time of 25 +/- 20 months (range: 9-60).
In this preliminary study, endovascular recanalization of native CTO showed satisfactory outcomes in patients with bypass graft occlusion.
本研究旨在报告经腔内开通下肢旁路移植闭塞中闭塞段的技术应用于治疗旁路移植闭塞后出现肢体严重缺血的临床应用价值。
对于旁路移植闭塞后出现肢体严重缺血的患者,目前尚没有关于最佳治疗方法的共识。
连续纳入 9 例因旁路移植闭塞导致肢体严重缺血的患者。应用腔内常规腔内及内膜下血管成形术和支架置入等技术尝试开通闭塞段。
旁路移植的平均年龄为 6.7 ± 7.3(1-24 个月),平均再次下肢旁路手术次数为 1.4 ± 0.5(1-2 次)。开通的血管包括髂股动脉(2 例)、髂动脉(2 例)、股浅动脉(3 例)、腘动脉(1 例)和胫腓动脉(1 例)。89%(8/9)的病例技术上获得成功,无并发症或重大心血管不良事件。血管再通后踝肱指数和足部皮肤灌注压显著升高,临床症状明显改善(Rutherford 分级:4.5 ± 1.1→0.9 ± 1.4,P<0.001)。在平均 25 ± 20 个月(9-60 个月)的随访期间,所有成功开通的病例均保肢成功。
在本初步研究中,经腔内开通下肢旁路移植闭塞段在治疗旁路移植闭塞后出现肢体严重缺血的患者中取得了满意的结果。