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[智利的罗斯手术]

[Ross operation in Chile].

作者信息

Turner G Eduardo, Muñoz C Rodrigo, Cumsille G Miguel, Iturra U Sebastián, Strodthoff R Pablo, Ulzurrún T Nicolás, Rodríguez A Juan

机构信息

Servicio de Cirugía Cardiovascular, Instituto Nacional del Tórax, Santiago, Chile.

出版信息

Rev Med Chil. 2010 Apr;138(4):413-20. Epub 2010 Jun 30.

Abstract

BACKGROUND

Donald Ross introduced the pulmonary autograft for aortic valve replacement with reconstruction of the right ventricular outflow tract with a homograft. Despite its advantages over conventional valve prostheses, the Ross Operation is performed in a minority of patients who need an aortic valve replacement throughout the world.

AIM

To report the operative and long term results of a series of patients subjected to Ross operation in Chile.

PATIENTS AND METHODS

Between 1996 and 2006, 131 patients aged 35+/-11 years (62% males) were subjected to an aortic root replacement with a pulmonary autograft and reconstruction of the right ventricular outflow tract with a pulmonary homograft. Seventy percent had congenital valve disease. Associated procedures were done in 39%. Patients were followed for a mean of 56+/-30 months.

RESULTS

Operative mortality was 2.3%. Two patients had the autografts replaced intraoperatively because of tears in the proximal suture line and one within a month of the operation after suffering autograft endocarditis. At last follow up all patients are in functional class 1 or 2. Autograft reoperations were done in two patients who developed dilation with valve regurgitation (both had aortic regurgitation as primary indication for aortic valve replacement). Three patients required reoperation for pulmonary homograft dysfunction. Another three patients had uneventful pregnancies with normal newborns. Actuarial freedom from any reoperation at 10 years is 93%.

CONCLUSIONS

The Ross Operation has low operative morbidity and mortality with excellent long term results. Reoperations have been rare within 10 years of follow up both for the autograft or the homograft.

摘要

背景

唐纳德·罗斯引入了肺动脉自体移植术用于主动脉瓣置换,并使用同种异体移植物重建右心室流出道。尽管与传统瓣膜假体相比具有优势,但在全世界需要进行主动脉瓣置换的患者中,接受罗斯手术的患者占少数。

目的

报告智利一系列接受罗斯手术患者的手术及长期结果。

患者与方法

1996年至2006年期间,131例年龄为35±11岁(62%为男性)的患者接受了肺动脉自体移植主动脉根部置换术及肺动脉同种异体移植右心室流出道重建术。70%患有先天性瓣膜疾病。39%的患者进行了相关手术。患者平均随访56±30个月。

结果

手术死亡率为2.3%。两名患者因近端缝线处撕裂在术中更换了自体移植物,一名患者在术后一个月内因自体移植物心内膜炎更换了自体移植物。在最后一次随访时,所有患者的心功能分级为1级或2级。两名出现瓣膜反流扩张的患者进行了自体移植物再次手术(两人均以主动脉反流作为主动脉瓣置换的主要指征)。三名患者因肺动脉同种异体移植物功能障碍需要再次手术。另外三名患者妊娠顺利,新生儿正常。10年时无需再次手术的精算生存率为93%。

结论

罗斯手术的手术发病率和死亡率较低,长期效果良好。在随访的10年内,自体移植物或同种异体移植物的再次手术都很少见。

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