Chen Zu-Yue, Hu Ying-Zhou, Zhang Yu-Hua, Jiang Hui-Hui, Hu Xin-Tian
Laboratory of Sensory-motor Integration Research, Kunming Institute of Zoology, the Chinese Academy of Sciences, Kunming 650223, China.
Dongwuxue Yanjiu. 2010 Jun;31(3):287-91. doi: 10.3724/SP.J.1141.2010.03287.
The saccadic system has anatomical and functional connections with the pupillary light reflex (PLR) system. But it is not known whether the saccadic system modulates the PLR system. To investigate this issue, it is necessary to understand whether the uneven light stimulus to retina and the near responses influence the change of pupil diameter. We designed a new behavioral method to investigate the issue on human subjects.
one eye of the subject was stimulated by pulse light stimulus from a horizontal linear array of light emitting diodes (LEDs) presented across visual field in an ocular mask. The changes of the eye position and pupil diameter of another eye were recorded by an infrared eye tracking system.
The relative constriction ratios of PLRs on the condition that the fixation points of subjects were in the nasal visual field were not significantly different from that the fixation points of subjects were in the temporal visual field(P=0.148, non-paired t test).
The influences from uneven light stimulus to retina and the near responses were eliminated by this method. The method can be used to study the modulation from the saccadic system on the pupillary light reflex system.
扫视系统与瞳孔光反射(PLR)系统存在解剖学和功能上的联系。但尚不清楚扫视系统是否会调节PLR系统。为了研究这个问题,有必要了解视网膜的不均匀光刺激和近反射是否会影响瞳孔直径的变化。我们设计了一种新的行为学方法来研究人类受试者的这个问题。
受试者的一只眼睛受到来自眼部面罩中横跨视野呈现的水平线性发光二极管(LED)阵列的脉冲光刺激。另一只眼睛的眼位和瞳孔直径变化由红外眼动追踪系统记录。
受试者注视点在鼻侧视野时PLR的相对收缩率与注视点在颞侧视野时相比无显著差异(P = 0.148,非配对t检验)。
该方法消除了视网膜不均匀光刺激和近反射的影响。该方法可用于研究扫视系统对瞳孔光反射系统的调节作用。