Riches N G, Loucas T, Baird G, Charman T, Simonoff E
Guy's and St Thomas' NHS Hospital Trust, Newcomen Centre, Guy's Hospital, London, SE1 9RT, UK.
J Commun Disord. 2011 Jan-Feb;44(1):23-36. doi: 10.1016/j.jcomdis.2010.06.003. Epub 2010 Jul 8.
Non-word repetition (NWR) was investigated in adolescents with typical development, Specific Language Impairment (SLI) and Autism Plus language Impairment (ALI) (n=17, 13, 16, and mean age 14;4, 15;4, 14;8 respectively). The study evaluated the hypothesis that poor NWR performance in both groups indicates an overlapping language phenotype (Kjelgaard & Tager-Flusberg, 2001). Performance was investigated both quantitatively, e.g. overall error rates, and qualitatively, e.g. effect of length on repetition, proportion of errors affecting phonological structure, and proportion of consonant substitutions involving manner changes. Findings were consistent with previous research (Whitehouse, Barry, & Bishop, 2008) demonstrating a greater effect of length in the SLI group than the ALI group, which may be due to greater short-term memory limitations. In addition, an automated count of phoneme errors identified poorer performance in the SLI group than the ALI group. These findings indicate differences in the language profiles of individuals with SLI and ALI, but do not rule out a partial overlap. Errors affecting phonological structure were relatively frequent, accounting for around 40% of phonemic errors, but less frequent than straight Consonant-for-Consonant or vowel-for-vowel substitutions. It is proposed that these two different types of errors may reflect separate contributory mechanisms. Around 50% of consonant substitutions in the clinical groups involved manner changes, suggesting poor auditory-perceptual encoding. From a clinical perspective algorithms which automatically count phoneme errors may enhance sensitivity of NWR as a diagnostic marker of language impairment.
Readers will be able to (1) describe and evaluate the hypothesis that there is a phenotypic overlap between SLI and Autism Spectrum Disorders (2) describe differences in the NWR performance of adolescents with SLI and ALI, and discuss whether these differences support or refute the phenotypic overlap hypothesis, and (3) understand how computational algorithms such as the Levenshtein Distance may be used to analyse NWR data.
对发育正常的青少年、特定语言障碍(SLI)青少年以及自闭症合并语言障碍(ALI)青少年(人数分别为17、13、16,平均年龄分别为14岁4个月、15岁4个月、14岁8个月)进行了非词重复(NWR)研究。该研究评估了以下假设:两组中NWR表现不佳表明存在重叠的语言表型(凯尔加德和塔杰-弗卢斯伯格,2001年)。从定量方面(如总体错误率)和定性方面(如长度对重复的影响、影响语音结构的错误比例以及涉及发音方式变化的辅音替换比例)对表现进行了研究。研究结果与之前的研究(怀特豪斯、巴里和毕晓普,2008年)一致,表明SLI组中长度的影响比ALI组更大,这可能是由于短期记忆限制更大。此外,对音素错误的自动计数显示SLI组的表现比ALI组更差。这些发现表明SLI和ALI个体在语言特征上存在差异,但不排除部分重叠。影响语音结构的错误相对频繁,约占音素错误的40%,但比直接的辅音对辅音或元音对元音替换频率低。有人提出,这两种不同类型的错误可能反映了不同的促成机制。临床组中约50%的辅音替换涉及发音方式变化,表明听觉感知编码较差。从临床角度来看,自动计数音素错误的算法可能会提高NWR作为语言障碍诊断标志物的敏感性。
读者将能够(1)描述和评估SLI与自闭症谱系障碍之间存在表型重叠的假设;(2)描述SLI和ALI青少年在NWR表现上的差异,并讨论这些差异是支持还是反驳表型重叠假设;(3)理解如何使用诸如莱文斯坦距离等计算算法来分析NWR数据。