Kronfli Rania, Bradnock Timothy J, Sabharwal Atul
Royal Hospital for Sick Children, Glasgow, UK.
Pediatr Surg Int. 2010 Sep;26(9):891-4. doi: 10.1007/s00383-010-2676-4. Epub 2010 Jul 30.
We reviewed our experience with gastroschisis (GS) complicated by intestinal atresia over the last 26 years. Our aim was to determine the effect of different management strategies employed and the morbidity associated with this condition in our unit.
A retrospective casenote review was carried out. Data regarding the operative management of the GS and atresia was recorded. Primary outcome measures included time to commence and establish full enteral feeds, duration of parenteral nutrition, complications and outcome.
Of 179 neonates with GS, 23 also had intestinal atresia. 13 underwent primary closure of the defect, 5 had patch closure and 5 had a silo placed. 4 atresias were 'missed' at first operation. The 19 recognised atresias were managed either by stoma formation, primary anastomosis or deferred management with subsequent primary anastomosis. There was wide variation in the outcomes of patients in each group.
Differences in outcome between the management strategies are likely to reflect an inherent variability in patient condition, site of atresia, and bowel suitability for anastomosis at first surgery, rather than the mode of surgical management. Individual management plans should be tailored to the clinical condition of each patient.
我们回顾了过去26年中腹裂(GS)合并肠闭锁的治疗经验。我们的目的是确定所采用的不同管理策略的效果以及我们科室中与这种情况相关的发病率。
进行了一项回顾性病例记录审查。记录了有关GS和闭锁手术管理的数据。主要结局指标包括开始并建立完全肠内喂养的时间、肠外营养的持续时间、并发症和结局。
在179例GS新生儿中,23例也患有肠闭锁。13例行缺损一期关闭,5例行补片关闭,5例行肠袋置入。4例闭锁在首次手术时“漏诊”。19例确诊的闭锁采用造口术、一期吻合术或延期处理并随后行一期吻合术。每组患者的结局差异很大。
管理策略之间的结局差异可能反映了患者病情、闭锁部位以及首次手术时肠道吻合适宜性的固有变异性,而非手术管理方式。应根据每位患者的临床情况制定个体化管理计划。