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腹主动脉瘤血管内修复治疗试验 1:是否改变了实践?

The EVAR Trial 1: has it led to a change in practice?

机构信息

Department of Vascular and Endovascular Surgery, University Hospitals of Leicester, Leicester Royal Infirmary, Leicester, UK.

出版信息

Surgeon. 2009 Dec;7(6):326-31. doi: 10.1016/s1479-666x(09)80104-2.

Abstract

OBJECTIVES

To assess whether the publication of the EVAR Trial 1 (June 2005) had an impact on practice in our centre.

METHODS

A retrospective study of all patients undergoing abdominal aortic aneurysm (AAA) repair in Leicester, from the year before publication of EVAR Trial 1 data to the year after (July 2004 - June 2006). Data from the study period was then compared with practice over the last six years (January 2000 - December 2006).

RESULTS

The proportion of endovascular aneurysm repairs (EVARs) did not change significantly in the year following publication of EVAR Trial 1 data (52% VS 57%, p=0.64). The mean age of patients offered open repair (OR) fell in the year following publication (69 years +/- 6.68 vs 72 years +/- 5.71, p<0.05). Despite this, there was no significant change in their fitness (physiological POSSUM scores: 19.2 +/- 3.91 vs 18.2 +/- 3.74, P=0.30). There was an overall increase in the percentage of EVARs in the years 2000 (28%) to 2006 (57%).

CONCLUSION

There was no significant difference in the percentage of EVARs between the two years of study. However, over the last six years, there has been an increasing number performed in our unit and we now do more EVARs than ORs.

摘要

目的

评估 EVAR 试验 1(2005 年 6 月)的发表是否对我们中心的实践产生了影响。

方法

对莱斯特所有接受腹主动脉瘤(AAA)修复的患者进行回顾性研究,时间范围为 EVAR 试验 1 数据发表前一年至发表后一年(2004 年 7 月至 2006 年 6 月)。然后将研究期间的数据与过去六年(2000 年 1 月至 2006 年 12 月)的实践进行比较。

结果

在 EVAR 试验 1 数据发表后的一年中,血管内动脉瘤修复(EVAR)的比例没有显著变化(52% VS 57%,p=0.64)。发表后一年接受开放修复(OR)的患者的平均年龄下降(69 岁 +/- 6.68 岁与 72 岁 +/- 5.71 岁,p<0.05)。尽管如此,他们的健康状况(生理 POSSUM 评分:19.2 +/- 3.91 与 18.2 +/- 3.74,P=0.30)没有显著变化。2000 年(28%)至 2006 年(57%),EVAR 的百分比总体增加。

结论

在研究的两年中,EVAR 的比例没有显著差异。然而,在过去的六年中,我们单位进行的 EVAR 数量有所增加,现在我们做的 EVAR 比 OR 多。

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