双侧纹状体苍白球齿状核钙质沉着症伴发作性运动诱发性运动障碍。

Bilateral striopallidodentate calcinosis with paroxysmal kinesigenic dyskinesia.

机构信息

Division of Child and Adolescent Neurology, Mayo Clinic, Rochester, MN, USA.

出版信息

Pediatr Neurol. 2010 Jul;43(1):46-8. doi: 10.1016/j.pediatrneurol.2010.03.013.

DOI:10.1016/j.pediatrneurol.2010.03.013

PMID:20682203

Abstract

Bilateral striopallidodentate calcinosis is characterized by calcification of the basal ganglia and other gray matter structures. We describe a 16-year-old boy with paroxysmal kinesigenic dyskinesia. He exhibited mineralization in the basal ganglia, posterior thalami, and dentate nuclei bilaterally, and was diagnosed with sporadic bilateral striopallidodentate calcinosis. The paroxysmal kinesigenic dyskinesia responded to low-dose treatment with carbamazepine (200 mg/day).

摘要

双侧纹状体苍白球齿状核钙化症的特征是基底节和其他灰质结构的钙化。我们描述了一名 16 岁的男孩，他患有发作性运动诱发性运动障碍。他表现为双侧基底节、后丘脑和齿状核的矿化，被诊断为散发性双侧纹状体苍白球齿状核钙化症。发作性运动诱发性运动障碍对卡马西平（200 毫克/天）的低剂量治疗有反应。