播散性组织胞浆菌病中的肛周溃疡

Perianal ulcer in disseminated histoplasmosis.

作者信息

Recondo G, Sella A, Ro J Y, Dexeus F H, Amato R, Kilbourn R

机构信息

Department of Medical Oncology, University of Texas M.D. Anderson Cancer Center, Houston 77030.

出版信息

South Med J. 1991 Jul;84(7):931-2. doi: 10.1097/00007611-199107000-00031.

DOI:10.1097/00007611-199107000-00031

PMID:2068646

Abstract

A 65-year-old man with stage I testicular seminoma, treated with surgery and radiation, had fever of unknown origin, adrenal insufficiency, and an isolated perianal ulcer. Tissue diagnosis of disseminated histoplasmosis was established by biopsy of the perianal ulcer, an unusual cutaneous manifestation of the disease. Treatment with amphotericin B resulted in rapid clinical improvement and complete healing of the perianal ulcer.

摘要

一名65岁患有I期睾丸精原细胞瘤的男性，接受了手术和放疗，出现不明原因发热、肾上腺功能不全以及孤立性肛周溃疡。通过肛周溃疡活检确诊为播散性组织胞浆菌病，这是该疾病一种不寻常的皮肤表现。使用两性霉素B治疗后临床症状迅速改善，肛周溃疡完全愈合。