[结外边缘区B细胞淋巴瘤（MALT型）及胃肠道弥漫性大B细胞淋巴瘤的病理学与鉴别诊断的当前研究进展]
[Current aspects of the pathology and differentiation of extranodal marginal zone B-cell lymphoma, MALT-Type, and gastrointestinal diffuse large B-cell lymphoma].
作者信息
Flossbach L, Kestler H A, Gress T M, Möller P, Barth T F
机构信息
Institut für Pathologie, Universitätsklinikum Ulm.
出版信息
Z Gastroenterol. 2010 Aug;48(8):833-8. doi: 10.1055/s-0029-1245421. Epub 2010 Aug 4.
The marginal zone B-cell lymphoma, MALT-type (MZBL, MT) is a low-grade B-cell lymphoma which is predominantly localised in the stomach with a typical morphology and cytogenetic pattern. The coexistence of a diffuse large B-cell lymphoma (DLBCL) with an MZBL, MT in the gastrointestinal tract is defined as a composite lymphoma (ComL) and represents a fascinating model of lymphoma progression. In this review we focus on current aspects regarding the molecular characterisation of MZBL, MT and gastrointestinal DLBCL and their mutual relationships.
边缘区B细胞淋巴瘤，MALT型（MZBL，MT）是一种低度恶性B细胞淋巴瘤，主要局限于胃部，具有典型的形态学和细胞遗传学特征。胃肠道中弥漫性大B细胞淋巴瘤（DLBCL）与MZBL，MT共存被定义为复合淋巴瘤（ComL），是淋巴瘤进展的一个有趣模型。在本综述中，我们重点关注MZBL，MT和胃肠道DLBCL的分子特征及其相互关系的当前研究进展。
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