Suppr超能文献

与接触血管紧张素转换酶抑制剂相关的胎儿病

[Fetopathy associated with exposure to angiotensin converting enzyme inhibitors].

作者信息

Neves Sérgio, Santos Raquel, Gomes Clara, Correia António Jorge

机构信息

Unidade de Nefrologia Pediátrica, Hospital Pediátrico de Coimbra, Coimbra.

出版信息

Acta Med Port. 2010 Jul-Aug;23(4):697-700. Epub 2010 Jul 30.

Abstract

Angiotensin Converting Enzyme Inhibitors (ACEI) are commonly used antihypertensive drugs, although contraindicated during pregnancy by fetopathy association such as renal dysgenesis, oligohydramnios, hipocalvaria, pulmonary hypoplasia, intrauterine growth restriction, and neonatal anuric renal failure. The authors present a clinical report of a child that developed neonatal anuric renal failure with peritoneal dialysis support by an in uterus exposure to ACEI with very good recovery. This case and literature review states the need to avoid ACEI prescription to Young women and it's suspension as soon as possible during pregnancy.

摘要

血管紧张素转换酶抑制剂(ACEI)是常用的抗高血压药物,尽管因与胎儿病变相关,如肾发育不全、羊水过少、颅骨发育不全、肺发育不全、宫内生长受限和新生儿无尿性肾衰竭等,在孕期禁用。作者报告了一例临床病例,一名儿童因子宫内接触ACEI而出现新生儿无尿性肾衰竭,在腹膜透析支持下恢复良好。该病例及文献综述指出,有必要避免给年轻女性开具ACEI处方,并在孕期尽快停用。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验