Epilepsy Center, Department of Neurology, University of Munich, Munich, Germany.
Epilepsy Behav. 2010 Oct;19(2):95. doi: 10.1016/j.yebeh.2010.06.034. Epub 2010 Aug 7.
Several observations make it worthwhile to take a closer look at postictal events, which are defined as manifestations of seizure-induced reversible alterations in neuronal function. The postictal period may adversely affect the quality of life, considering the duration and severity of postictal events. The postictal period is often longer than the seizure itself. Postictal events such as psychosis, confusion, aphasia, and paresis can be incapacitating. On a more positive side, the increased seizure threshold seen during the postictal period may offer clues for development of more effective seizure treatment. In this issue, experts in the field elucidate the postictal period from different viewpoints, including the mechanism of the postictal period, its diagnostic challenges, and its management.
有几点观察结果值得我们更深入地研究癫痫发作后状态，后者被定义为由神经元功能障碍引起的癫痫发作后可逆性改变的表现。考虑到癫痫发作后状态的持续时间和严重程度，其可能会对生活质量产生不利影响。癫痫发作后状态通常比癫痫发作本身持续时间更长。癫痫发作后状态可引起如精神病、意识模糊、失语和瘫痪等使人丧失能力的表现。从更积极的方面来看，癫痫发作后状态期间观察到的癫痫发作阈值增加，可能为开发更有效的癫痫治疗方法提供线索。本期中，该领域的专家从不同角度阐述了癫痫发作后状态，包括其发生机制、诊断挑战和管理。
