Sohpal Vipan Kumar, Dey Apurba, Singh Amarpal
Department of Chemical and Biotechnology, Beant College of Engineering and Technology, Gurdaspur, Punjab 143 521, India.
Int J Comput Biol Drug Des. 2010;3(1):68-88. doi: 10.1504/IJCBDD.2010.034466. Epub 2010 Aug 5.
Bioinformatics is the application of computational techniques to analyse the wet lab information associated with biomolecules on a commercial scale. Today's it concentrate on structural biology, genomics to gene expression studies. In this review we discuss the main principles that desirable bioinformatics analyses, sequence alignment and phylogenetic analysis from biological databases that are commonly used and examine some of the studies that are being conducted, particularly with reference to Human Herpes Simplex Virus (HHV). Finally provide an introduction and overview of the bioinformatics tools and software used for sequence alignment.
生物信息学是指应用计算技术在商业规模上分析与生物分子相关的湿实验室信息。如今,它专注于结构生物学、基因组学以及基因表达研究。在本综述中,我们讨论了理想的生物信息学分析、常用生物数据库中的序列比对和系统发育分析的主要原理,并审视了正在进行的一些研究,特别是关于人类单纯疱疹病毒(HHV)的研究。最后介绍并概述了用于序列比对的生物信息学工具和软件。