法国一项全国性调查 7 年的结果：医院诊治的卒中与短暂性脑缺血发作的时间趋势。

Time trends in hospital-referred stroke and transient ischemic attack: results of a 7-year nationwide survey in France.

机构信息

Dijon Stroke Registry, University Hospital and Faculty of Medicine of Dijon, University of Burgundy, 3 Rue du Faubourg Raines, Dijon, France.

出版信息

Cerebrovasc Dis. 2010;30(4):346-54. doi: 10.1159/000319569. Epub 2010 Aug 5.

DOI:10.1159/000319569

PMID:20693789

Abstract

BACKGROUND

Nationwide evaluations of the burden of stroke are scarce. We aimed to evaluate trends in stroke and transient ischemic attack (TIA) hospitalization, in-hospital case fatality rates (CFRs) and mortality rates in France during 2000-2006.

METHODS

Hospitalizations for stroke and TIA were determined from National Hospital Discharge Diagnosis Records that used the International Classification of Disease, 10th revision, codes I60, I61, I63, I64, G45, G46. CFRs and mortality rates were estimated from the national death certificates database.

RESULTS

The total number of stays for stroke increased between 2000 and 2006 (88,371 vs. 92,118) contrasting with a decrease in that for TIA. The age-standardized (European population) hospitalization rates for TIA decreased in men (52.2 vs. 44.5/100,000/year, p = 0.002), whereas they remained stable in women (32.4 vs. 31.0/ 100,000/year). Concerning stroke, a decrease in hospitalization rates was observed in both men (from 135.3 to 123.4/ 100,000/year, p < 0.001) and women (from 85.1 to 80.7, p < 0.001). Whatever the age group and the sex, a sharp decrease in in-hospital stroke CFRs was noted. In addition, a 23% decrease in mortality rates was observed. This decrease was greater in patients >65 years.

CONCLUSION

Our results demonstrate a decline in hospitalization rates for stroke, and in both stroke CFRs and mortality rates between 2000 and 2006. Improvements in stroke prevention and acute stroke care may have contributed to these results, and may have been initiated by recent advances in health policy with regard to this disease in France.

摘要

背景

全国范围内对卒中负担的评估很少。我们旨在评估 2000-2006 年法国卒中与短暂性脑缺血发作（TIA）住院率、住院病死率（CFR）和死亡率的趋势。

方法

从国家住院诊断记录中确定卒中与 TIA 的住院病例，这些记录使用国际疾病分类，第 10 版（ICD-10）的 I60、I61、I63、I64、G45 和 G46 代码。CFR 和死亡率是从国家死亡证明数据库中估算出来的。

结果

2000 年至 2006 年间，卒中总住院人数增加（88371 例 vs. 92118 例），而 TIA 住院人数则减少。男性 TIA 的年龄标准化（欧洲人口）住院率下降（52.2 例/100000/年 vs. 44.5/100000/年，p=0.002），而女性则保持稳定（32.4 例/100000/年 vs. 31.0/100000/年）。至于卒中，男性（从 135.3 例/100000/年降至 123.4/100000/年，p<0.001）和女性（从 85.1 例/100000/年降至 80.7/100000/年）的住院率均下降。无论年龄组和性别如何，住院卒中 CFR 都急剧下降。此外，死亡率下降了 23%。这一降幅在 65 岁以上的患者中更大。