血清成分异常水平对抗生素活性的影响。
Effect of abnormal levels of serum components on antibiotic activity.
作者信息
Plotkin B J, Wright M, Lima A, Gruenberg L
机构信息
Department of Microbiology, Chicago College of Osteopathic Medicine, Downers Grove, Illinois 60515.
出版信息
Antimicrob Agents Chemother. 1991 Apr;35(4):767-9. doi: 10.1128/AAC.35.4.767.
Abstract
Antibiotic activity in serum from a model for type II diabetes was similar to that in normal sera or media containing cholesterol but lacking glucose, insulin, or both. The ratio of effects of broth plus obese-rat serum to effects of broth plus lean-rat serum supplemented with cholesterol approached or equaled 1.
摘要
来自II型糖尿病模型血清中的抗生素活性与正常血清或含有胆固醇但缺乏葡萄糖、胰岛素或两者皆缺的培养基中的抗生素活性相似。肉汤加肥胖大鼠血清的效果与肉汤加补充胆固醇的瘦大鼠血清的效果之比接近或等于1。
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本文引用的文献
1
Amikacin pharmacokinetics in morbidly obese patients.阿米卡星在病态肥胖患者中的药代动力学。
Am J Hosp Pharm. 1980 Apr;37(4):519-22.
2
Effect of obesity on gentamicin pharmacokinetics.肥胖对庆大霉素药代动力学的影响。
J Clin Pharmacol. 1981 Jul;21(7):288-93. doi: 10.1002/j.1552-4604.1981.tb01769.x.
3
Vancomycin pharmacokinetics in normal and morbidly obese subjects.正常和病态肥胖受试者的万古霉素药代动力学。
Antimicrob Agents Chemother. 1982 Apr;21(4):575-80. doi: 10.1128/AAC.21.4.575.
4
Pharmacokinetics of drugs in obesity.肥胖人群中药物的药代动力学
Clin Pharmacokinet. 1982 Mar-Apr;7(2):108-24. doi: 10.2165/00003088-198207020-00002.
5
Interaction of plasma proteins and lipoproteins with amphotericin B.血浆蛋白和脂蛋白与两性霉素B的相互作用。
J Infect Dis. 1984 Jun;149(6):986-97. doi: 10.1093/infdis/149.6.986.
6
New concepts in the pathogenesis and treatment of noninsulin-dependent diabetes mellitus.
Am J Med. 1983 Jan 17;74(1A):52-81. doi: 10.1016/0002-9343(83)90654-x.
7
Genetic obesity in rats. I. The effects of food restriction on body composition and hypothalamic function.大鼠的遗传性肥胖。I. 食物限制对身体成分和下丘脑功能的影响。
Metabolism. 1973 Mar;22(3):435-42. doi: 10.1016/0026-0495(73)90035-8.
8
The influence of obesity on health (second of two parts).肥胖对健康的影响（两部分中的第二部分）
N Engl J Med. 1974 Aug 1;291(5):226-32. doi: 10.1056/NEJM197408012910504.
9
Comparison of three cholesterol-lowering diets in normolipidemic men.
JAMA. 1986 Nov 7;256(17):2351-5.
10
Influence of obesity on drug disposition.肥胖对药物处置的影响。
Clin Pharm. 1987 Sep;6(9):706-14.
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