Department of Orthopedic Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, 1665 Kongjiang Road, 200092 Shanghai, China.
Eur Spine J. 2011 Mar;20(3):351-7. doi: 10.1007/s00586-010-1544-1. Epub 2010 Aug 8.
Cervical spondylotic amyotrophy is characterized with weakness and wasting of upper limb muscles without sensory or lower limb involvement. Two different mechanisms have been proposed in the pathophysiology of cervical spondylotic amyotrophy. One is selective damage to the ventral root or the anterior horn, and the other is vascular insufficiency to the anterior horn cell. Cervical spondylotic amyotrophy is classified according to the most predominantly affected muscle groups as either proximal-type (scapular, deltoid, and biceps) or distal-type (triceps, forearm, and hand). Although cervical spondylotic amyotrophy always follows a self-limited course, it remains a great challenge for spine surgeons. Treatment of cervical spondylotic amyotrophy includes conservative and operative management. The methods of operative management for cervical spondylotic amyotrophy are still controversial. Anterior decompression and fusion or laminoplasty with or without foraminotomy is undertaken. Surgical outcomes of distal-type patients are inferior to those of proximal-type patients.
脊髓型颈椎病性肌萎缩症的特征是上肢肌肉无力和萎缩,无感觉或下肢受累。脊髓型颈椎病性肌萎缩症的病理生理学有两种不同的机制。一种是腹侧根或前角的选择性损伤,另一种是前角细胞的血管不足。根据最主要受累的肌肉群,脊髓型颈椎病性肌萎缩症可分为近端型(肩胛带、三角肌和肱二头肌)或远端型(肱三头肌、前臂和手)。尽管脊髓型颈椎病性肌萎缩症总是呈自限性病程,但它仍然是脊柱外科医生面临的一大挑战。脊髓型颈椎病性肌萎缩症的治疗包括保守治疗和手术治疗。脊髓型颈椎病性肌萎缩症的手术治疗方法仍存在争议。可进行前路减压融合或椎板成形术,伴或不伴椎间孔切开术。远端型患者的手术效果不如近端型患者。