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阿尔茨海默病的磁共振成像:从诊断到治疗评估。

Magnetic resonance imaging of Alzheimer's disease: from diagnosis to therapeutic evaluation.

机构信息

Beijing Military General Hospital, Beijing, China.

出版信息

Chin J Integr Med. 2010 Jun;16(3):276-82. doi: 10.1007/s11655-010-0276-8. Epub 2010 Aug 8.

Abstract

Alzheimer's disease (AD) is a devastating late-life dementia that produces progressive loss of memory and mental faculties in elderly people. It is important to identify the earliest evidence of AD and to monitor the development of this disease for us to make positive response to its management. Magnetic resonance imaging (MRI) is powerful to image the tissue or organ without damnification. MRI can be employed to diagnose the early AD development and monitor the key biomarker development in AD. MRI may be helpful not only in diagnosing early AD, but also in evaluating its development. This article reviews the progress of MRI on the diagnosis and detection of AD, and makes comments on its therapeutic application.

摘要

阿尔茨海默病(AD)是一种破坏性的老年痴呆症,会导致老年人记忆力和智力逐渐丧失。重要的是要识别 AD 的最早证据,并监测这种疾病的发展,以便我们对其进行积极的管理。磁共振成像(MRI)是一种强大的无损伤成像技术。MRI 可用于诊断早期 AD 发展并监测 AD 中的关键生物标志物发展。MRI 不仅有助于诊断早期 AD,还有助于评估其发展。本文综述了 MRI 在 AD 诊断和检测方面的研究进展,并对其治疗应用进行了评价。

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