Department of Emergency Medicine, Cleveland Clinic Foundation, Cleveland, OH, USA.
Rev Cardiovasc Med. 2010;11 Suppl 2:S45-50. doi: 10.3909/ricm11S2S0001.
The role of cardiac biomarkers in the diagnosis, risk stratification, and treatment of patients with chest pain and suspected acute coronary syndromes (ACS) has continued to evolve. Although it is clear that troponin (Tn) measurement provides independent prognostic information in patients with suspected ACS, it is less well established that early B-type natriuretic peptide (BNP) measurement provides additional incremental prognostic information above and beyond electrocardiography and Tn measurement. It is useful to identify patients at high risk for adverse events through measurement of Tn and BNP levels so that timely treatment decisions can be made.
心脏生物标志物在胸痛和疑似急性冠状动脉综合征(ACS)患者的诊断、风险分层和治疗中的作用不断演变。尽管肌钙蛋白(Tn)测量在疑似 ACS 患者中提供独立的预后信息已很明确,但早期 B 型利钠肽(BNP)测量在心电图和 Tn 测量之外提供额外的增量预后信息则不太确定。通过测量 Tn 和 BNP 水平来识别发生不良事件风险高的患者是有用的,以便及时做出治疗决策。