Niţuc Ecaterina, Năstase V, Mihăilescu G, Chioveanu Diana
Gr. T. Popa University of Medicine and Pharmacy, Iaşi School of Pharmacy, Discipline of Analytical Chemistry.
Rev Med Chir Soc Med Nat Iasi. 2010 Apr-Jun;114(2):580-6.
Ground water is a major source of public supply for the rural population and in some areas, it is only source of available water. It is well known the toxic action of nitrate upon organisms, by formatting methemoglobin and N-nitroso compounds.
In this study it was investigated the presence of nitrates and nitrites in same well waters, mountain and hill areas in Neamţ district. The chemical parameters were carried out by following standard methods. The statistical analysis includes descriptive statistics of the water quality parameters.
It is noticed high values of the nitrate concentrations, over Maximum Admissible Concentration (MAC), explained by excessive use of agricultural synthetic fertilizer and telluric nitrogen. It was registered a number of 38 cases of methemoglobinemia in small children with artificial nutrition, all cases from hill area. The maximum methemoglobin level was 60% and the minimum value of nitrate concentration in the water samples was 396 mg NO3-/L.
We established a direct correlation between the level of methemoglobin and the nitrate concentrations in water samples. It is recommended the use well waters with maximum 48 mg/L nitrates content.
地下水是农村人口公共供水的主要来源，在某些地区，它是唯一可用的水源。硝酸盐通过形成高铁血红蛋白和N-亚硝基化合物对生物体产生毒性作用，这是众所周知的。
在本研究中，调查了尼亚姆茨区山区和丘陵地区同一井水硝酸盐和亚硝酸盐的存在情况。化学参数按照标准方法进行测定。统计分析包括水质参数的描述性统计。
注意到硝酸盐浓度高于最大允许浓度（MAC），这是由于过量使用农业合成肥料和土壤氮所致。在人工喂养的幼儿中记录了38例高铁血红蛋白血症病例，所有病例均来自丘陵地区。高铁血红蛋白的最高水平为60%，水样中硝酸盐浓度的最小值为396mg NO3-/L。
我们确定了高铁血红蛋白水平与水样中硝酸盐浓度之间的直接相关性。建议使用硝酸盐含量最高为48mg/L的井水。
