Tan Tock Seng Hospital, Orthopaedics, Singapore.
Int J Rheum Dis. 2010 Aug;13(3):235-9. doi: 10.1111/j.1756-185X.2010.01477.x.
Patients with systemic lupus erythematosus (SLE), rheumatoid arthritis (RA) and ankylosing spondylitis (AS) often require total hip arthroplasties. We present a retrospective review of 32 total hip arthroplasties (THA) performed for patients with SLE, RA or AS from 2003 to 2008 in a tertiary hospital in Singapore.
A total of 323 THAs performed between January 2003 to December 2008 were traced and cases of arthroplasties performed for such patients were isolated. Pre- and post-operative range of motion, Harris hip score, limb length discrepancies and complications were studied.
Twenty-six patients aged 24-66 years (mean 47 years) were reviewed, with two AS patients (7.7%), 16 RA patients (61.5%), seven SLE patients (26.9%) and one patient (3.8%) with both RA and SLE. Thirty-two THA operations were conducted with six patients requiring bilateral THAs. The average follow-up was 3.3 years. Mean Harris hip score for 25 patients (one excluded due to patient expiry 2 month post-surgery) improved from 41.3 to 86.53 (P < 0.05). Mean pre-operative hip flexion improved from 61.3 degrees (0-120) to 89.7 degrees (30-120) (P < 0.05). Seventeen cases had preoperative limb length discrepancies (median 1 cm) which were all corrected. There were no implants loosening, infective arthritis, dislocations or neurovascular injuries documented.
Our series demonstrated the excellent outcome of THA for patients with chronic autoimmune arthropathies at the time of follow-up. Careful patient selection remains a priority as long-term outcomes for such patients of a significantly younger population is yet to be determined.
患有系统性红斑狼疮(SLE)、类风湿关节炎(RA)和强直性脊柱炎(AS)的患者通常需要接受全髋关节置换术。我们对 2003 年至 2008 年在新加坡一家三级医院接受全髋关节置换术(THA)的 32 例 SLE、RA 或 AS 患者进行了回顾性研究。
共追踪到 2003 年 1 月至 2008 年 12 月期间进行的 323 例 THA,分离出为这些患者进行的关节置换术病例。研究了术前和术后的活动范围、Harris 髋关节评分、肢体长度差异和并发症。
共 26 例 24-66 岁(平均 47 岁)的患者接受了回顾性分析,其中 2 例 AS 患者(7.7%)、16 例 RA 患者(61.5%)、7 例 SLE 患者(26.9%)和 1 例同时患有 RA 和 SLE 的患者(3.8%)。32 例 THA 手术中有 6 例需要双侧 THA。平均随访 3.3 年。25 例患者的 Harris 髋关节评分平均从 41.3 提高到 86.53(P<0.05)。术前髋关节屈曲的平均角度从 61.3°(0-120)提高到 89.7°(30-120)(P<0.05)。17 例术前存在肢体长度差异(中位数 1cm),均得到纠正。未发现假体松动、感染性关节炎、脱位或神经血管损伤。
在随访时,我们的系列研究表明 THA 治疗慢性自身免疫性关节病的效果非常好。只要尚未确定此类人群中年龄明显较小的患者的长期预后,仔细选择患者仍然是首要任务。