严重高铁血红蛋白血症后牙麻醉：关于新生儿普罗替卡因诱导高铁血红蛋白血症的警告。

Severe methemoglobinemia after dental anesthesia: a warning about propitocaine-induced methemoglobinemia in neonates.

机构信息

Department of Anesthesiology, Japanese Red Cross Society Wakayama Medical Center, 4-20 Komatsubara-dori, Wakayama, Wakayama 640-8558, Japan.

出版信息

J Anesth. 2010 Dec;24(6):935-7. doi: 10.1007/s00540-010-1004-4. Epub 2010 Aug 13.

DOI:10.1007/s00540-010-1004-4

PMID:20706742

Abstract

Methemoglobinemia is a fatal complication of local anesthesia. We describe a case report of female neonate who developed severe methemoglobinemia after extraction of neonatal teeth conducted with general anesthesia plus local injection of Citanest-Octapressin(®) (propitocaine of approximately 10 mg/kg). Central cyanosis appeared within an hour after surgery. The percentage of methemoglobin reached up to 43.9%. Not only pediatric dentists but also anesthesiologists generally agree with the idea that local anesthesia provides various benefits in painful procedures in neonates. However, this case may serve as a warning when using Citanest-Octapressin(®), which is still commercially available for neonatal patients.

摘要

高铁血红蛋白血症是局部麻醉的一种致命并发症。我们描述了一例女性新生儿的病例报告，该新生儿在全身麻醉加局部注射 Citanest-Octapressin(®)（约 10mg/kg 的丙哌卡因）进行新生儿牙齿拔除后发生严重的高铁血红蛋白血症。手术后一小时内出现中央发绀。高铁血红蛋白百分比高达 43.9%。不仅儿科牙医，而且麻醉师普遍认为，局部麻醉在新生儿疼痛治疗中具有多种益处。然而，当使用仍可用于新生儿患者的 Citanest-Octapressin(®) 时，此病例可能会发出警告。