浅黄马杜拉放线菌INA 292细胞壁磷壁酸和肽聚糖的结构特征

Structural features of cell wall teichoic acid and peptidoglycan of Actinomadura cremea INA 292.

作者信息

Potekhina N V, Naumova I B, Shashkov A S, Terekhova L P

机构信息

Department of Microbiology, Moscow State University, USSR.

出版信息

Eur J Biochem. 1991 Jul 15;199(2):313-6. doi: 10.1111/j.1432-1033.1991.tb16126.x.

DOI:10.1111/j.1432-1033.1991.tb16126.x

PMID:2070791

Abstract

The teichoic acid from the cell wall of Actinomadura cremea INA 292 has an unusual structure, being a poly(galactosylglycerol phosphate) chain with glycerol phosphate groups. Monomeric units of 1-O, beta-D-galactopyranosylglycerol monophosphate are joined in the polymer by phosphodiester links involving the glycerol C3 and the galactose C6 atoms. Approximately every second galactosyl substituent has a glycerol phosphate residue at its C3 atom. The teichoic acid structure was established by chemical analysis and 13C-NMR spectroscopy. There also is a peptidoglycan belonging to the A1 gamma type: as well as meso-2,6-diaminopimelic acid it contains small amounts of the LL form and glycine.

摘要

来自奶油马杜拉放线菌INA 292细胞壁的磷壁酸具有不寻常的结构，是一条带有甘油磷酸基团的聚（半乳糖基甘油磷酸）链。1-O-β-D-吡喃半乳糖基甘油单磷酸的单体单元通过涉及甘油C3和半乳糖C6原子的磷酸二酯键连接在聚合物中。大约每隔一个半乳糖基取代基在其C3原子处有一个甘油磷酸残基。磷壁酸的结构通过化学分析和13C-NMR光谱确定。还存在一种属于A1γ型的肽聚糖：除了内消旋-2,6-二氨基庚二酸外，它还含有少量的LL型和甘氨酸。