School of Health Information Sciences, The University of Texas Health Science Center at Houston, 7000 Fannin Street, Suite 600, Houston, TX 77030, USA.
Neuroimaging Clin N Am. 2010 Aug;20(3):367-78. doi: 10.1016/j.nic.2010.05.001.
Treatment of glioblastoma multiforme remains a major challenge despite advances in standard therapy, including surgery, radiation, and chemotherapy. The field of nanomedicine is expected to have a major impact on the treatment and management of brain tumors. Over the past decade, significant efforts have been made in using nanoparticles for diagnosis and treatment of brain tumors. One class of nanoparticles, liposomes, have received considerable attention for use as nanocarriers for delivery of therapeutics and contrast agents. The purpose of this article is to present the advances in the design and functional characteristics of liposomes for applications in brain tumor imaging.
尽管在标准治疗（包括手术、放疗和化疗）方面取得了进展，但多形性胶质母细胞瘤的治疗仍然是一个主要挑战。纳米医学领域有望对脑肿瘤的治疗和管理产生重大影响。在过去的十年中，人们在使用纳米粒子诊断和治疗脑肿瘤方面做出了巨大努力。一类纳米粒子，即脂质体，因其作为治疗药物和对比剂递送的纳米载体的应用而受到广泛关注。本文旨在介绍脂质体在脑肿瘤成像应用中的设计和功能特性方面的进展。
