Shigematsu T, Kaneko S, Miyazawa N, Tabuchi H, Yorozu T, Tashiro M, Saito N
Department of Anesthesiology, Tokyo Metropolitan Ohtsuka Hospital.
Masui. 1991 Mar;40(3):361-6.
The effects of enflurane (E) and halothane (H) on hemodynamics were studied during the inhalation of 2MAC of each anesthetic before the surgery. Mean arterial pressure (MAP), heart rate (HR), cardiac index (CI), systemic vascular resistance (SVRI) and stroke volume index (SVI) were measured noninvasively using automatic blood pressure manometer and ultrasonic Doppler method (Accucom). MAP decreased with both E and H, but the decrement was bigger with E. CI and SVI decreased with H, although increased with E. SVRI was unchanged with H, but decreased with E. These results indicate that enflurane causes the depression of blood pressure mostly by the decrease of afterload during the induction of anesthesia.