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南非眼部肉样瘤病患者的临床特征。

Clinical profile of ocular sarcoidosis in a South Indian patient population.

机构信息

Vittala International Institute of Ophthalmology & Prabha Eye Clinic and Research Center, Bangalore, India.

出版信息

Ocul Immunol Inflamm. 2010 Oct;18(5):362-9. doi: 10.3109/09273948.2010.495813.

Abstract

AIM

To report the ocular and systemic features in patients with definite and presumed sarcoidosis presenting to a tertiary referral eye center in south India.

MATERIALS AND METHODS

Retrospective observational case series. Records of 51 patients with diagnosis of sarcoidosis were retrieved. A complete ophthalmic evaluation and systemic examination by a pulmonologist with appropriate laboratory investigations were done in all patients. Results were statistically analyzed using SPSS software.

RESULTS

The mean age group was 45.14 ± 10.91 years. Females were more common and 31 cases were biopsy proven. Panuveitis and thoracic involvement was the most common ophthalmic and systemic manifestations of sarcoid respectively. Posterior synechiae, granulomatous keratic precipitates, increased anterior chamber reaction, and cystoid macular edema were significantly more common in those presenting initially to an ophthalmologist.

CONCLUSIONS

Sarcoidosis is increasingly recognized in south India as well. A complete review of systems with appropriate investigations is essential to prevent ocular or systemic morbidity.

摘要

目的

报告在印度南部一家三级转诊眼科中心就诊的明确和疑似类肉瘤病患者的眼部和全身特征。

材料与方法

回顾性观察性病例系列。检索了 51 例诊断为类肉瘤病的患者记录。对所有患者进行全面的眼科评估和由肺病专家进行的全身检查,并进行了适当的实验室检查。使用 SPSS 软件进行统计学分析。

结果

平均年龄组为 45.14±10.91 岁。女性更为常见,31 例经活检证实。全葡萄膜炎和胸部受累分别是类肉瘤病最常见的眼部和全身表现。初次就诊于眼科医生的患者中,后粘连、肉芽肿性角膜沉淀物、前房反应增加和囊样黄斑水肿更为常见。

结论

类肉瘤病在印度南部也越来越被认识。全面的系统回顾和适当的检查对于预防眼部或全身发病率至关重要。

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