聚脱氧核糖核苷酸激活腺嘌呤 A2A 受体增加血管内皮生长因子并防止实验性精索静脉曲张大鼠睾丸损伤。
Activation of adenosine A2A receptors by polydeoxyribonucleotide increases vascular endothelial growth factor and protects against testicular damage induced by experimental varicocele in rats.
机构信息
Department of Clinical and Experimental Medicine and Pharmacology, University of Messina, Messina, Italy.
出版信息
Fertil Steril. 2011 Mar 15;95(4):1510-3. doi: 10.1016/j.fertnstert.2010.07.1047. Epub 2010 Aug 24.
Abstract
In rat experimental varicocele, polydeoxyribonucleotide (PDRN) induces vascular endothelial growth factor (VEGF) production, thereby enhancing testicular function. This may point to a new therapeutic approach in human varicocele.
摘要
在大鼠精索静脉曲张实验中，聚脱氧核糖核苷酸（PDRN）可诱导血管内皮生长因子（VEGF）的产生，从而增强睾丸功能。这可能为人类精索静脉曲张提供一种新的治疗方法。
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