Department of Anesthesiology and Pain Medicine, Harborview Medical Center, University of Washington, Seattle, Washington 98104, USA.
J Clin Neurosci. 2010 Dec;17(12):1583-4. doi: 10.1016/j.jocn.2010.04.009. Epub 2010 Aug 25.
We describe a 13-year-old child who developed inadvertent intraoperative cerebral oxygen desaturation attributed to empiric hyperventilation during posterior fossa craniotomy, diagnosed by jugular venous oximetry. Although restoration of normocapnia at age-appropriate mean arterial blood pressure improved jugular venous saturation (SjvO), it remained below acceptable values. Transcranial-Doppler (TCD) ultrasonography-guided stepwise increase in mean arterial pressure led to a linear increase in the mean flow velocity of the middle cerebral artery and SjvO₂ to desirable values. Intraoperative SjvO₂ monitoring and TCD ultrasonography may be utilized together to individualize hemodynamic targets and ventilation parameters and maintain adequate cerebral oxygenation during paediatric craniotomies.
我们描述了一例 13 岁儿童,在行后颅窝开颅术时因经验性过度通气而导致术中脑氧饱和度意外下降,通过颈静脉血氧饱和度(jugular venous oximetry)诊断。尽管在年龄相应的平均动脉血压下恢复正常碳酸血症可改善颈静脉饱和度(SjvO),但仍低于可接受值。经颅多普勒(TCD)超声引导下逐步增加平均动脉压可导致大脑中动脉平均流速和 SjvO₂线性增加至理想值。术中 SjvO₂监测和 TCD 超声检查可联合用于个体化血流动力学目标和通气参数,并在小儿开颅术中维持足够的脑氧合。