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[降钙素治疗反射性交感神经营养不良患者]

[The calcitonin treatment of patients with algodystrophy].

作者信息

Solarova P, Kŭnev K

出版信息

Vutr Boles. 1990;29(5):102-5.

PMID:2080602
Abstract

23 patients with algodystrophy, 28 up to 82 years of age, were treated with calcitonin during the period 1978-1988 and the effect of the treatment is discussed. The treatment was carried out with the drug Myacalcic "Sandoz" in a daily dose of 100 IU, administered intramuscularly every day in the course of 10 days. The following clinical parameters were followed up: pain, swelling, functional capacity, skin (dystrophic) changes. The patients are classified in 2 groups in relation to the results: I. group--acute stage and II. group--chronic stage of the disease. The pain was favourably influenced in both groups by the Myacalcic treatment. In the acute stage the swelling was favourably influenced in 81% of the patients, the skin changes in 89%, the functional capacity was improved 1.64 times. In the chronic stage the swelling was reduced in 25% of the patients, there was no effect on the dystrophic changes and the functional capacity decreased in spite of the treatment.

摘要

1978年至1988年期间,对23例年龄在28岁至82岁之间的反射性交感神经营养不良患者使用降钙素进行了治疗,并对治疗效果进行了讨论。治疗采用“山德士”公司生产的密钙息,日剂量为100国际单位,连续10天每天肌肉注射。对以下临床参数进行了随访:疼痛、肿胀、功能能力、皮肤(营养不良性)变化。根据结果将患者分为两组:第一组——急性期和第二组——疾病的慢性期。密钙息治疗对两组患者的疼痛均产生了有利影响。在急性期,81%的患者肿胀得到改善,89%的患者皮肤变化得到改善,功能能力提高了1.64倍。在慢性期,25%的患者肿胀减轻,对营养不良性变化无影响,尽管进行了治疗,功能能力仍下降。

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