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膀胱憩室及其与恶性肿瘤的关联:一项尸体解剖学研究

Urinary bladder diverticulum and its association with malignancy: an anatomical study on cadavers.

作者信息

Rajini T, Kumar Bhardwaj Ajay, V Jayanthi, Kalyani Rao P, Singh Gajendra

机构信息

Department of Anatomy, Vydehi Institute of Medical Sciences and Research Centre, Whitefield, Bangalore, Karnataka, India.

出版信息

Rom J Morphol Embryol. 2010;51(3):543-5.

Abstract

Present work was directed to study the prevalence and anatomical basis of diverticulum formation and its association with malignancy inside the urinary bladder on cadavers. Urinary bladder diverticulum and its complications including malignancy has been reported by different authors based on their study on radiological findings and endoscopy. Present study was undertaken on cadavers to meet the aforementioned objectives. Thirty properly embalmed cadavers (19 males and 11 females) of different ages were dissected. Sagittal section of pelvis was studied. Urinary bladder was incised to expose the interior and it was examined for the presence of diverticulum (including number and location). Detailed history of the cause of death of cadavers with diverticulum was studied to determine how many of them suffered from urinary bladder diverticular carcinoma. 23.4% cadavers (31.6% males and 9.1% females) showed presence of urinary bladder diverticulum. The location of the diverticulum in all the cadavers was on superior and lateral side of the ureteric opening on the posterior surface of the urinary bladder. Diverticulum of one male cadaver aged 74 years was complicated by malignancy. Our study observed greater prevalence of diverticulum formation as compared to previous reports. In the present work, 14.3% diverticulum of the urinary bladder showed malignant change, which is more than earlier reports in the literature. Urinary bladder diverticulum should neither be neglected nor ignored. Appropriate early treatment (including the cause) of the diverticulum should be undertaken to avoid complications like malignancy which will finally ensure longevity.

摘要

目前的研究旨在探讨尸体膀胱憩室形成的患病率、解剖学基础及其与膀胱内恶性肿瘤的关系。不同作者基于对放射学检查结果和内窥镜检查的研究,报道了膀胱憩室及其包括恶性肿瘤在内的并发症。本研究在尸体上进行,以实现上述目标。解剖了30具经过适当防腐处理的不同年龄尸体(19例男性和11例女性)。研究了骨盆的矢状切面。切开膀胱以暴露内部,并检查是否存在憩室(包括数量和位置)。研究了有憩室尸体的详细死亡原因病史,以确定其中有多少人患有膀胱憩室癌。23.4%的尸体(男性为31.6%,女性为9.1%)存在膀胱憩室。所有尸体中憩室的位置均在膀胱后表面输尿管开口的上方和外侧。一名74岁男性尸体的憩室并发恶性肿瘤。我们的研究观察到,与先前的报告相比,憩室形成的患病率更高。在本研究中,14.3%的膀胱憩室出现了恶性变化,这比文献中早期的报告要多。膀胱憩室既不应被忽视也不应被无视。应采取适当的早期治疗(包括病因)来避免诸如恶性肿瘤等并发症,这最终将确保长寿。

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