Chhablani Jay, Romanzo Antonio, Balmer Aubin, Pica Alessia, Gaillard Marie-Claire, Cozza Raffaele, Moeckli Raphaël, Munier Francis L
Vitreo-Retina Services, L V Prasad Eye Institute, Hyderabad, Andhra Pradesh, India.
Ophthalmic Genet. 2010 Dec;31(4):190-2. doi: 10.3109/13816810.2010.499888. Epub 2010 Sep 1.
A 2-year-old boy with syndromic bilateral retinoblastoma resulting from a (del(13)(q12.3q14.3)) developed a recurrent tumor measuring 2.3 X 2.3 mm at the ora serrata 15 months following last treatment.
Ultrasound biomicroscopy (UBM) revealed a mass invading the ciliary body 6.6 mm in diameter associated with a localized supraciliary effusion.
Complete tumor regression was achieved 1 month after brachytherapy with a (106)Ruthenium plaque. There was no recurrence at 16 months.
This is the first clinical demonstration of supraciliary effusion in recurrent retinoblastoma. Brachytherapy appears to be effective in the treatment of this type of recurrence.