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右旋糖酐/透明质酸用于儿童膀胱输尿管反流的内镜治疗——单名外科医生的6年经验

Endoscopic Treatment of Vesicoureteral Reflux in Children with Dextranomer/Hyaluronic Acid-A Single Surgeon's 6-Year Experience.

作者信息

Chen Hou-Chuan, Yeh Chou-Ming, Chou Chia-Man

机构信息

Division of Pediatric Surgery, Department of Surgery, Taichung Veterans General Hospital, 160, Sec 3, Chung-Kang Road, Taichung 40705, Taiwan.

出版信息

Diagn Ther Endosc. 2010;2010. doi: 10.1155/2010/278012. Epub 2010 Aug 5.

Abstract

Endoscopic treatment for vesicoureteral reflux (VUR) has become an established alternative to long-term antibiotic prophylaxis and ureteral reimplantation. We present the outcome of endoscopic treatment with dextranomer/hyaluronic acid copolymer (Deflux) for VUR in children by a single surgeon at our institute from October 2003 to October 2009. We reviewed the cases of 150 patients (total 239 ureters), 56 girls (37%) and 94 boys (63%), with a mean age of 2.2 years and a median followup of 2.5 years (range 3-68 months). Among the 239 ureters treated, 67.4% (161/239) were cured with a single injection, and a second and third injection raised the cure rate to 86.6% (207/239) and 88.3% (211/239), respectively. None had postoperative ureteral obstruction.

摘要

内镜治疗膀胱输尿管反流(VUR)已成为长期抗生素预防和输尿管再植术之外一种成熟的替代方法。我们展示了2003年10月至2009年10月期间,我院一名外科医生使用葡聚糖omer/透明质酸共聚物(Deflux)对儿童VUR进行内镜治疗的结果。我们回顾了150例患者(共239条输尿管)的病例,其中女孩56例(37%),男孩94例(63%),平均年龄2.2岁,中位随访时间2.5年(范围3 - 68个月)。在接受治疗的239条输尿管中,单次注射治愈的占67.4%(161/239),第二次和第三次注射后治愈率分别提高到86.6%(207/239)和88.3%(211/239)。无一例发生术后输尿管梗阻。

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