生活在不同深度的同属鱼类乳酸脱氢酶的压力适应性差异。

Pressure-adaptive differences in lactate dehydrogenases of congeneric fishes living at different depths.

作者信息

Siebenaller J, Somero G N

出版信息

Science. 1978 Jul 21;201(4352):255-7. doi: 10.1126/science.208149.

DOI:10.1126/science.208149

PMID:208149

Abstract

The muscle-type (M4) lactate dehydrogenases of Sebastolobus altivelis, a deep-water scorpaenid, and S. alascanus, a shallower species, are electrophoretically indistinguishable, yet differ in pressure sensitivities. The lactate dehydrogenase of S. altivelis exhibits lower pressure sensitivities of substrate and coenzyme binding and catalytic rate. Such apparently pressure-adaptive kinetic properties may be important for establishing species depth zonation patterns in the ocean.

摘要

深水鲉科鱼类高体 Sebastolobus altivelis 和较浅水域物种阿拉斯加 Sebastolobus alascanus 的肌肉型（M4）乳酸脱氢酶在电泳上无法区分，但在压力敏感性方面存在差异。高体 Sebastolobus altivelis 的乳酸脱氢酶在底物和辅酶结合以及催化速率方面表现出较低的压力敏感性。这种明显的压力适应性动力学特性可能对确定海洋中的物种深度分区模式很重要。