Zhang Dan, Li Zhaoge, Bao Xinguang, Li Jiangbo, Liang Haihua, Duan Kangmin, Shen Lixin
Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, Faculty of Life Sciences, Northwest University, Xi'an 710069, China.
Sheng Wu Gong Cheng Xue Bao. 2010 Jun;26(6):726-34.
Polycyclic aromatic hydrocarbons (PAHs) are toxic pollutants that exist extensively in the environment. Microbial degradation is the main pathway of PAHs eradication in natural environment and therefore is of importance to investigate. Advancement has been made in recent years regarding the PAHs molecular degradation mechanisms in bacteria. In this review, we summarized some of the research progresses in microbial PAHs biodegradation pathways (including salicylate pathway and protocatechuate pathway), key enzymes (nah-like, phn, phd, nid and nag) and genes involved. Emphasis was given on naphthalene and phenanthrene which were often used as the representatives of PAHs. It is likely that the new information will promote further research and applications of microbial PAHs biodegradation technology.
多环芳烃(PAHs)是广泛存在于环境中的有毒污染物。微生物降解是自然环境中PAHs消除的主要途径,因此对其进行研究具有重要意义。近年来,在细菌中PAHs分子降解机制方面取得了进展。在本综述中,我们总结了微生物PAHs生物降解途径(包括水杨酸途径和原儿茶酸途径)、关键酶(nah样、phn、phd、nid和nag)以及相关基因的一些研究进展。重点讨论了经常用作PAHs代表的萘和菲。这些新信息可能会促进微生物PAHs生物降解技术的进一步研究和应用。