Fromer Leonard
Department of Family Medicine, UCLA School of Medicine, Los Angeles, CA, USA.
South Med J. 2010 Oct;103(10):1038-44. doi: 10.1097/SMJ.0b013e3181ebec5c.
Asthma is a chronic disease characterized by airway inflammation and hyperresponsiveness and is associated with significant yet avoidable mortality and morbidity resulting in considerable individual and societal burden. Inhaled corticosteroids are the most effective class of controller medication available today for treating persistent asthma and are the evidence-based guideline-recommended first-line treatment for controlling asthma. Although inhaled corticosteroids have proven to reduce asthma-related exacerbations that lead to hospitalizations and death, recent studies have shown that only a small percentage of patients receive appropriate treatment and monitoring for their asthma. Delivering optimal asthma management requires an understanding and application of basic science and evidence-based guidelines in clinical practice. Management of a chronic disease in the primary care setting requires overcoming several barriers due to competing priorities and time constraints of the physician, as well as the reluctance of patients to actively participate in their own care. However, evidence has shown that the patient-centered medical home model can overcome some of these issues and improve patient outcomes and adherence to therapy.
哮喘是一种以气道炎症和高反应性为特征的慢性疾病,与显著但可避免的死亡率和发病率相关,给个人和社会带来相当大的负担。吸入性糖皮质激素是目前治疗持续性哮喘最有效的一类控制药物,是循证指南推荐的控制哮喘的一线治疗方法。尽管吸入性糖皮质激素已被证明可减少导致住院和死亡的哮喘相关加重发作,但最近的研究表明,只有一小部分患者得到了针对其哮喘的适当治疗和监测。实现最佳的哮喘管理需要在临床实践中理解和应用基础科学及循证指南。在初级保健环境中管理慢性病需要克服几个障碍,这是由于医生面临相互竞争的优先事项和时间限制,以及患者不愿积极参与自身护理。然而,有证据表明,以患者为中心的医疗家庭模式可以克服其中一些问题,并改善患者的治疗效果和治疗依从性。