Garkavenko V V, Limanskaia L I, Vasil'eva R A, Vashchenko E A
Fiziol Zh (1978). 1990 Nov-Dec;36(6):23-7.
Human evoked potentials (EP) to paired somatosensory pain stimuli were recorded from the vertex. Amplitude of the N150 and P250 components of the second EP decreased within 600-1000 ms interstimulus interval. The depression occurred was more intensive with an increase of the first (conditioning) stimulus strength. As a rule, depression of N150 component was more pronounced. Selective averaging of EPs indicated that, when the stimulus intensity was stable, variations in the amplitudes of identical components in response to the first and second stimuli were not usually negatively correlated; positive correlation was frequently found. This can be regarded as a proof that there is no direct relation between the inhibitory after-processes in the cellular generators of the studied EP components and the degree of their previous activation. Such variations can reflect the sequence of periods of an increase and a decrease in the generator activity under conditions of stable stimulus intensity.
从头顶记录人类对成对体感疼痛刺激的诱发电位（EP）。在刺激间隔600 - 1000毫秒内，第二个EP的N150和P250成分的振幅降低。随着第一个（条件性）刺激强度的增加，所发生的抑制作用更强。通常，N150成分的抑制更为明显。EP的选择性平均表明，当刺激强度稳定时，对第一和第二个刺激作出反应的相同成分的振幅变化通常不呈负相关；经常发现呈正相关。这可以被视为一个证据，即在所研究的EP成分的细胞发生器中的抑制后过程与其先前的激活程度之间没有直接关系。这种变化可以反映在刺激强度稳定的条件下，发生器活动增加和减少的时间段顺序。
