Arnlind Marianne Heibert, Nokela Mika, Ehrs Per-Olof, Wikström Jonsson Eva
Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden.
Prim Care Respir J. 2010 Dec;19(4):383-9. doi: 10.4104/pcrj.2010.00046.
To explore the factor structure of asthma severity and asthma control and to compare the results of different approaches to asthma severity classification on the distribution of costs of asthma medication.
Comparison of four different approaches to asthma severity classification and factor analysis of asthma control descriptors. A correlation analysis between costs and the different approaches to severity classification was performed.
The factor analysis suggests that asthma control consists of at least two factors. Four approaches to severity classification were explored and all except the 'GINA EXPANDED' classification tended to place patients in the most severe category. The pharmaceutical costs varied between 0 and 75 SEK per day (0 and 5.31 GBP; 0 and 7.68 EURO).
There is a considerable overlap between asthma control and asthma severity. None of the approaches used in this study present a superior satisfactory solution to the classification problem.
探讨哮喘严重程度和哮喘控制的因素结构,并比较不同哮喘严重程度分类方法对哮喘药物治疗费用分布的影响。
比较四种不同的哮喘严重程度分类方法,并对哮喘控制指标进行因素分析。对费用与不同严重程度分类方法之间进行相关性分析。
因素分析表明,哮喘控制至少由两个因素组成。研究了四种严重程度分类方法,除“GINA扩展版”分类外,其他方法往往会将患者归为最严重的类别。药物费用每天在0至75瑞典克朗之间(0至5.31英镑;0至7.68欧元)。
哮喘控制和哮喘严重程度之间存在相当大的重叠。本研究中使用的方法均未为分类问题提供一个优越的令人满意的解决方案。