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Menopause. 2010 Sep-Oct;17(5):908-16. doi: 10.1097/gme.0b013e3181dbee1b.
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Eszopiclone improves insomnia and depressive and anxious symptoms in perimenopausal and postmenopausal women with hot flashes: a randomized, double-blinded, placebo-controlled crossover trial.艾司佐匹克隆改善围绝经期和绝经后伴有热潮红的妇女的失眠及抑郁和焦虑症状:一项随机、双盲、安慰剂对照交叉试验。
Am J Obstet Gynecol. 2010 Feb;202(2):171.e1-171.e11. doi: 10.1016/j.ajog.2009.10.868. Epub 2009 Dec 24.
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围绝经期睡眠障碍的评估与管理。

Evaluation and management of sleep disturbance during the menopause transition.

机构信息

Center for Women's Mental Health, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

出版信息

Semin Reprod Med. 2010 Sep;28(5):404-21. doi: 10.1055/s-0030-1262900. Epub 2010 Sep 15.

DOI:10.1055/s-0030-1262900
PMID:20845239
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3736837/
Abstract

Sleep disturbances in midlife women are common and have been associated with the menopause transition itself, symptoms of hot flashes, anxiety and depressive disorders, aging, primary sleep disorders (i.e., obstructive sleep apnea, periodic limb movement disorder), comorbid medical conditions and medications, as well as with psychosocial and behavioral factors. Because there are several common sources of sleep problems in midlife women, the cause of an individual woman's sleep disturbance may be multifactorial. Effective behavioral and pharmacological therapies are available to treat sleep disturbances of different etiologies. This review provides an overview of different types of sleep disturbance occurring in midlife women and presents data supporting the use of hormone therapy, hypnotic agents, and behavioral strategies to treat sleep problems in this population. The review aims to equip clinicians evaluating menopause-age women with the knowledge and evaluation tools to diagnose, engage sleep experts where appropriate, and treat sleep disturbance in this population. Sleep disorders in midlife women should be treated because substantial improvements in quality of life and health outcomes are achievable.

摘要

中年女性睡眠障碍很常见,与绝经过渡本身、热潮红症状、焦虑和抑郁障碍、衰老、原发性睡眠障碍(即阻塞性睡眠呼吸暂停、周期性肢体运动障碍)、合并症和药物治疗以及心理社会和行为因素有关。由于中年女性有多种常见的睡眠问题来源,因此,个别女性睡眠障碍的原因可能是多因素的。现已有有效的行为和药物治疗方法可用于治疗不同病因的睡眠障碍。本综述概述了中年女性中发生的不同类型的睡眠障碍,并提供了支持使用激素治疗、催眠药物和行为策略来治疗该人群睡眠问题的数据。本综述旨在为评估更年期女性的临床医生提供知识和评估工具,以便在适当的情况下诊断、寻求睡眠专家的帮助,并治疗该人群的睡眠障碍。治疗中年女性的睡眠障碍很有必要,因为可以显著提高生活质量和健康结果。