Theravance, Inc., South San Francisco, CA 94080, USA.
Diagn Microbiol Infect Dis. 2010 Oct;68(2):181-5. doi: 10.1016/j.diagmicrobio.2010.05.008.
During phase 3 clinical studies of telavancin for treatment of complicated skin and skin structure infections, a total of 1530 aerobic Gram-positive isolates were identified at baseline. The majority of these strains were Staphylococcus aureus (n = 1214; 62% methicillin-resistant). All isolates were inhibited by ≤ 1 μg/mL of telavancin.
在替拉万星治疗复杂性皮肤和皮肤软组织感染的 3 期临床试验中,共有 1530 株需氧革兰阳性菌在基线时被鉴定。这些菌株主要为金黄色葡萄球菌(n=1214;耐甲氧西林株占 62%)。所有分离株均被 ≤1μg/ml 的替拉万星抑制。