Noh Chee Ho, Cheung Dae Young, Kim Tae Ho, Jun Eun Jung, Lee In Kyu, Kim Jin Il, Cho Se Hyun, Park Soo Heon, Han Joon Yeol, Kim Jae Kwang
Departments of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea.
Korean J Gastroenterol. 2010 Sep;56(3):201-4. doi: 10.4166/kjg.2010.56.3.201.
The inverse correlation of appendectomy and ulcerative colitis is well known, but the effect of appendectomy on the clinical course of ulcerative colitis remains unclear. Although the majority of opinions were negative for the therapeutic advantage of appendectomy in patients with ulcerative colitis, advocates for positive effect of appendectomy have been proposed in a few case reports and a prospective study from Western countries. We herein report a case of ulcerative colitis who experienced clinical remission after appendectomy for acute appendicitis. The patient was 35 year old male and had been managed with immunosuppressant before appendectomy. The very acute change in clinical course and a long period of remission after appendectomy highly suggest the therapeutic effect of appendectomy for ulcerative colitis.
阑尾切除术与溃疡性结肠炎的负相关关系已为人熟知,但阑尾切除术对溃疡性结肠炎临床病程的影响仍不明确。尽管大多数观点认为阑尾切除术对溃疡性结肠炎患者并无治疗优势,但一些西方国家的病例报告和前瞻性研究中也有人主张阑尾切除术具有积极作用。我们在此报告一例溃疡性结肠炎患者,其在因急性阑尾炎接受阑尾切除术后实现了临床缓解。该患者为35岁男性,在阑尾切除术前一直使用免疫抑制剂治疗。临床病程的急剧变化以及阑尾切除术后的长期缓解强烈提示阑尾切除术对溃疡性结肠炎具有治疗效果。