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活体义眼虹膜。

A 'living' prosthetic iris.

机构信息

Department of Engineering Physics, Advanced Photonics Concepts Laboratory, Ecole Polytechnique de Montreal, Montreal, Quebec, Canada.

出版信息

Eye (Lond). 2010 Nov;24(11):1716-23. doi: 10.1038/eye.2010.128. Epub 2010 Sep 17.

Abstract

AIM

To design and demonstrate dynamic pupils, which react to light for use with ocular prostheses.

METHODS

The realism of ocular prostheses is limited by the immobility of the pupil. Our solution is to use a liquid crystal display (LCD) in the prosthesis to vary the pupil size as a function of the ambient light. Several liquid crystal cells were fabricated and tested for survivability through the ocular prosthesis manufacturing process. The dynamic pupil is controlled by a novel and entirely autonomous, self-powered passive electronic circuit using a solar cell, matching the minimum diameter of the pupil.

RESULTS

The first LCD surviving the rugged conditions of the ocular prosthesis manufacturing steps and an entirely passive circuit controlling the pupil have been demonstrated for the first time to our knowledge. A design for a complete prosthesis with a dynamic pupil has been proposed. Finally, a standard device for the mass production of ocular prostheses is presented.

CONCLUSION

We have shown that a practical solution for an autonomous self-powered dynamic pupil is possible, given the constraints of size, fabrication process, weight, cost and manufacturability on a mass scale. We envision that the LCD could be mass produced, and only the final steps for the integration of the iris matched to a patient would be necessary before assembly using standard processing steps for the production of the prosthesis. Using a clinical trial, we hope to demonstrate that the dynamic pupil will have a positive impact on the quality of life of patients.

摘要

目的

设计并展示动态瞳孔,使其对光做出反应,用于眼部假肢。

方法

眼部假肢的逼真度受到瞳孔固定不动的限制。我们的解决方案是在假肢中使用液晶显示器(LCD),根据环境光的变化来改变瞳孔大小。我们制造了几个液晶单元,并对它们在眼部假肢制造过程中的生存能力进行了测试。动态瞳孔由一个新颖的、完全自主的、自供电的无源电子电路控制,该电路使用太阳能电池,与瞳孔的最小直径相匹配。

结果

据我们所知,这是首次展示出经受住眼部假肢制造步骤苛刻条件的第一块幸存的 LCD 和控制瞳孔的完全无源电路。提出了带有动态瞳孔的完整假肢设计。最后,还介绍了一种用于眼部假肢大规模生产的标准设备。

结论

我们已经证明,在大规模生产中,考虑到尺寸、制造工艺、重量、成本和可制造性的限制,自主自供电的动态瞳孔的实用解决方案是可行的。我们设想可以大规模生产 LCD,并且在使用用于假肢生产的标准处理步骤进行组装之前,只需要进行最后一步将虹膜与患者相匹配的集成。我们希望通过临床试验证明,动态瞳孔将对患者的生活质量产生积极影响。

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