Zehlicke T, Just T, Specht O, Schmidt W, Sass W, Moss C, Pau H-W
Bundeswehrkrankenhaus Hamburg, HNO, Hamburg.
Laryngorhinootologie. 2011 Jan;90(1):26-9. doi: 10.1055/s-0030-1265167. Epub 2010 Sep 16.
Middle ear pressure depends widely on the function of the eustachian tube. Tube dysfunction is often a trigger for middle ear diseases like chronic otitis media but also for barotrauma. Patients with impaired tubal function should not be exposed to situations with extreme pressure changes. Until today, there is no valid examining method for long-time measuring of the development of middle ear pressure.
The basic idea was to develop a thin flexible film with integrated strain gauges made of platinum and gold, which can be applied directly on the surface of the tympanic membrane. Using these, shifts or distensions of the tympanic membrane in a temporal bone model can be measured and documented.
We were able to show that the measuring system was sensitive enough to register pressure variations in the middle ear volume of a temporal bone model. While using a full bridge design of the strain gauge resistors it could be shown that the measuring voltage of the strain gauges were in phase of the pressure measurement curve or according to the positioning in opposite phase. In single resistor mode the measurement were not so positioning depended. Measuring tympanic membrane movement in case of perforation was feasible.
To improve the longtime stability of the strain gauge film the next development step will be to make a new design with Konstantan resistors (CU-Ni-Mn). After a testing period, longtime measurements in clinical studies will follow.
中耳压力在很大程度上取决于咽鼓管的功能。咽鼓管功能障碍通常是慢性中耳炎等中耳疾病的诱因,也是气压伤的诱因。咽鼓管功能受损的患者不应暴露于压力急剧变化的环境中。直到如今,尚无有效的方法可长期测量中耳压力的变化情况。
基本思路是研发一种带有集成铂和金应变片的薄柔性膜,该膜可直接应用于鼓膜表面。利用这些应变片,可测量并记录颞骨模型中鼓膜的移位或扩张情况。
我们能够证明该测量系统足够灵敏,能够记录颞骨模型中耳腔的压力变化。当采用应变片电阻的全桥设计时,可以看出应变片的测量电压与压力测量曲线同相或根据位置反相。在单电阻模式下,测量结果对位置的依赖性没那么强。在鼓膜穿孔的情况下测量鼓膜运动是可行的。
为提高应变片薄膜的长期稳定性,下一步将采用康铜电阻(铜镍锰合金)进行新的设计。经过测试期后,将开展临床研究中的长期测量。