Yang Guo-Yuan, Liao Meng, Liu Long-Qian
Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu 610041, China.
Sichuan Da Xue Xue Bao Yi Xue Ban. 2010 Jul;41(4):652-5.
To investigate the contrast sensitivities of the fellow eyes in children with anisometropic and strabismic amblyopia.
A retrospective study was undertaken. Medical records containing contrast sensitivity data of the fellow eyes in 107 children with anisometropic amblyopia, 110 children with strabismic amblyopia, and 30 normal children were retrieved. The contrast sensitivities of the fellow eyes in those children were compared using independent t-test and one-way analysis of variance (ANOVA) with post hoc (modified LSD) multiple comparison test.
Contrast sensitivity functions of the fellow eyes of children with anisometropic and strabismic amblyopia were weaker than those of the controls. The fellow eyes of children with moderate and severe strabismic amblyopia had better contrast sensitivities than those with anisometropic amblyopes. In strabismic amblyopic children, the contrast sensitivities of the fellow eyes grew with the degree of amblyopia. Occlusion therapy did not change contrast sensitivities of the fellow eyes.
The abnormal intraocular interactions between amblyopic and nonamblyopic "normal" eyes decrease the contrast sensitivity functions of the fellow eyes. Compared with anisometropic amblyopic children, the fellow eyes of children with moderate and severe strabismic amblyopia show more superiority in the binocular competition. Occlusion therapy may not depress contrast sensitivities of the fellow eyes in children with amblyopia.
研究屈光参差性弱视和斜视性弱视患儿健眼的对比敏感度。
进行一项回顾性研究。检索了107例屈光参差性弱视患儿、110例斜视性弱视患儿和30例正常儿童健眼的对比敏感度数据的病历。使用独立t检验和单因素方差分析(ANOVA)以及事后(修正LSD)多重比较检验对这些儿童健眼的对比敏感度进行比较。
屈光参差性弱视和斜视性弱视患儿健眼的对比敏感度函数比对照组弱。中度和重度斜视性弱视患儿的健眼对比敏感度比屈光参差性弱视患儿的健眼更好。在斜视性弱视儿童中,健眼的对比敏感度随弱视程度增加。遮盖疗法并未改变健眼的对比敏感度。
弱视眼与非弱视“正常”眼之间异常的眼内相互作用降低了健眼的对比敏感度函数。与屈光参差性弱视儿童相比,中度和重度斜视性弱视儿童的健眼在双眼竞争中表现出更多优势。遮盖疗法可能不会降低弱视儿童健眼的对比敏感度。