单壁碳纳米管的抗菌活性：长度效应。

Antimicrobial activity of single-walled carbon nanotubes: length effect.

机构信息

Biomanufacturing Research Institute and Technology Enterprises (BRITE) and Department of Pharmaceutical Sciences, North Carolina Central University, Durham, North Carolina 27707, USA.

出版信息

Langmuir. 2010 Oct 19;26(20):16013-9. doi: 10.1021/la103110g.

DOI:10.1021/la103110g

PMID:20849142

Abstract

This study investigated the effect of SWCNTs' length on their antimicrobial activity to bacterial cells in suspensions. Three different lengths of SWCNTs (<1 μm, 1-5 μm, and ∼5 μm) were tested. At same weight concentration, longer SWCNTs exhibited stronger antimicrobial activity. The fluorescence and SEM images revealed that the longer SWCNTs aggregated with bacterial cells more effectively, whereas short length SWCNTs tended to aggregate themselves without involving many bacterial cells. Moreover, longer SWCNTs exhibited more pronounced concentration-dependence and treatment time-dependence on their antimicrobial activity.

摘要

本研究考察了 SWCNTs 长度对其在悬浮液中抗菌活性的影响。测试了三种不同长度的 SWCNTs（<1 μm、1-5 μm 和 ∼5 μm）。在相同重量浓度下，较长的 SWCNTs 表现出更强的抗菌活性。荧光和 SEM 图像显示，较长的 SWCNTs 更有效地与细菌细胞聚集，而短长度的 SWCNTs 往往自行聚集而不涉及许多细菌细胞。此外，较长的 SWCNTs 表现出更明显的浓度依赖性和处理时间依赖性抗菌活性。